Manchester United take on Stoke in the League Cup at the Britannia Stadium, and Danny Welbeck is once again named up front, albeit this time with Anderson taking Wayne Rooney's place in the teamsheet.
There is also a start for Ashley Young, with Phil Jones and Tom Cleverley in midfield. Darren Fletcher is on the bench once more, as is Shinji Kagawa and Wilfried Zaha.
Stoke, meanwhile, rotate some players but have former United defender Ryan Shawcross in defence. Asmir Begovic is rested for Thomas Sorensen, but Peter Crouch and Stephen Ireland both start.
Manchester United starting lineup: David De Gea; Rafael, Chris Smalling, Jonny Evans, Patrice Evra; Antonio Valencia, Tom Cleverley, Phil Jones, Anderson, Ashley Young; Danny Welbeck.
Subs: Sam Johnstone, Chicharito, Nani, Darren Fletcher, Alexander Büttner, Wilfried Zaha, Shinji Kagawa.
Stoke City starting lineup: Thomas Sorensen; Geoff Cameron, Ryan Shawcross (c), Marc Wilson, Erik Pieters; Jonathan Walters, Wilson Palacios, Stephen Ireland, Glenn Whelan, Oussama Assaidi; Peter Crouch