Fellaini looked like he could miss out after picking up a back spasm in midweek, though has clearly recovered. Adnan Januzaj also returns after being bizarrely omitted from the Champions League defeat away at Olympiacos.
Elsewhere, Chris Smalling and Phil Jones are the chosen centre-back pairing, with Nemanja Vidić on the bench and Rio Ferdinand nowhere to be seen. Rafael, thankfully, returns to his position at right-back.
With West Brom struggling and new boss Pepe Mel coming under fire, we can't surely mess this one up, can we? ...
Manchester United confirmed starting lineup: David De Gea; Patrice Evra, Chris Smalling, Phil Jones, Rafael da Silva; Marouane Fellaini, Michael Carrick; Adnan Januzaj, Wayne Rooney, Juan Mata; Robin van Persie.
Subs: Anders Lindegaard, Ryan Giggs, Nemanja Vidić, Ashley Young, Darren Fletcher, Shinji Kagawa, Danny Welbeck.
West Bromwich Albion confirmed starting lineup: Ben Foster; Liam Ridgewell, Jonas Olsson, Gareth McAuley, Steven Reid; Youssouf Mulumbu, Claudio Yacob; Chris Brunt, Zoltán Gera, Morgan Amalfitano; Victor Anichebe.