United are still without Luke Shaw, but Paddy McNair and Marcos Rojo's injuries both continue, meaning Ashley Young is likely to deputise at left-back again.
Youngsters Sam Johnstone, Sean Goss, Andreas Pereira and Guillermo Varela are all included in the provisional squad, and Anthony Martial and Memphis are also included.
Another defensive change from the Southampton game might be that Antonio Valencia, who started against Ipswich in midweek, continues at right-back.
You can read Jack Sargeant's excellent match preview on the Busby Babe here.
When: Saturday 26 September 2015, 3pm GMT, 10am EST
Where: Old Trafford, Manchester
How to watch: NBCSN (US)/Dodgy stream, which is illegal so don't do it (UK)
How to watch online: NBC Sports Live Extra (US)
Subs: Romero, Jones, Herrera, Schweinsteiger, Pereira, Young, Fellaini
Sunderland: Pantilimon, Jones, van Aanholt, O'Shea (c), Kaboul, Cattermole, M'Vila, Johnson, Toivonen, Lens, Borini
Subs: Larsson, Gomez, Defoe, Coates, Yedlin, Fletcher, Mannone