Manchester United take on Sunderland with the chance to go top of the league. United that is, Sunderland are desperately trying to cling to life (but that won't stop them looking like world-beaters).
United are still without Luke Shaw, but Paddy McNair and Marcos Rojo's injuries both continue, meaning Ashley Young is likely to deputise at left-back again.
Youngsters Sam Johnstone, Sean Goss, Andreas Pereira and Guillermo Varela are all included in the provisional squad, and Anthony Martial and Memphis are also included.
Another defensive change from the Southampton game might be that Antonio Valencia, who started against Ipswich in midweek, continues at right-back.
You can read Jack Sargeant's excellent match preview on the Busby Babe here.
When: Saturday 26 September 2015, 3pm GMT, 10am EST
Where: Old Trafford, Manchester
How to watch: NBCSN (US)/Dodgy stream, which is illegal so don't do it (UK)
How to watch online: NBC Sports Live Extra (US)
#mufc XI: De Gea; Valencia, Smalling, Blind, Darmian; Schneiderlin, Carrick; Mata, Rooney, Memphis; Martial. pic.twitter.com/jiFjETuiFj— The Busby Babe (@TheBusbyBabe) September 26, 2015
Subs: Romero, Jones, Herrera, Schweinsteiger, Pereira, Young, Fellaini
Sunderland: Pantilimon, Jones, van Aanholt, O'Shea (c), Kaboul, Cattermole, M'Vila, Johnson, Toivonen, Lens, Borini
Subs: Larsson, Gomez, Defoe, Coates, Yedlin, Fletcher, Mannone