Manchester United play Southampton with a relatively small injury list. Only Nick Powell, Bastian Schweinsteiger and Phil Jones are confirmed injury doubts.
That means that the horrendously bad Marouane Fellaini should keep his place in midfield, despite Andreas Pereira and Ander Herrera both being better options to partner Morgan Schneiderlin.
Herrera should continue as a number 10, and after Jesse Lingard's anonymous performance against Liverpool, Juan Mata may make a return on the right wing.
Ashley Young came off injured against Liverpool, and if he is unable to return to fitness in time for the weekend's match, expect Cameron Borthwick-Jackson to feature.
Wayne Rooney and Anthony Martial should make up the attack, with Rooney sensibly kept as far away from having to pass the ball as possible.
Subs: Romero, McNair, Pereira, Carrick, Januzaj, Memphis, Lingard