Chris Smalling, Marouane Fellani and Antonio Valencia could return for Manchester United after making their way back from injury.
Manchester United's poor defensive showing against Watford should see Smalling replace Marcos Rojo in central defence, and Antonio Valencia could replace Guillermo Varela who, along with Matteo Darmian, has been unable to make an especially strong case to start at right-back for the longer term.
Marouane Fellaini should be less likely to replace Ander Herrera and Morgan Schneiderlin, who have been enormously less incompetent than the Belgian. However, with attacking injuries affecting the team, don't rule out Louis van Gaal trying to ruin everything for United.
In attack, Marcus Rashford could start in attack, with Juan Mata, Anthony Martial and Memphis in support. Senior players Bastian Schweinsteiger and Wayne Rooney are still out for the foreseeable future, and Luke Shaw is the obvious longest term injury for United.
Subs: Romero, McNair, Lingard, Fosu-Mensah, Darmian, Fellaini, Valencia.