Wayne Rooney has been rumoured to make a return, possibly, at Spurs, though it seems unlikely, and his ability is severely compromised as he regains fitness. Luke Shaw is back on the training field, but it is at the very early stage of his recovery still, so is unlikely to feature again until next season.
Bastian Schweinsteiger is still out with a knee injury, and Ashley Young is unfit, too. Will Keane and Phil Jones may also miss the match.
That means that, given United won against Everton last week, they will probably line up in much the same way. Marouane Fellaini has been, enjoyably, not featuring of late. Long may that continue.
As ever, a health warning: there's almost no point predicting what Louis van Gaal will do, there's every chance a hot pot with play central defence.
Subs: Romero, Rojo, Fosu-Mensah, Herrera, Fellaini, Memphis, Rooney